Droplet Microfluidics

Advanced Chemical Sensor Technology

Droplet Microfluidics

Droplets are defined here as water droplets dispersed in an immiscible oil phase or oil droplets dispersed in water. These droplets are contained and motivated through microfluidic conduits having dimensions most easily measured in microns. Droplets microfluidics is emerging as a reliable engineering tool for performing biological operations such as analyte encapsulation, sampling, metering, dilution, reaction, separation and detection.

Publications:

1. Continuous measurement of enzymatic kinetics in droplet flow for point-of-care monitoring,  Analyst, 2016,141, 3266-3273, DOI: 10.1039/C6AN00620E

2. A Nano LC-MALDI Mass Spectrometry Droplet Interface for the Analysis of Complex Protein Samples. PLoS ONE, 2013,  8(5): e63087. doi:10.1371/journal.pone.0063087

3. Continuous online microdialysis using microfluidic sensors: dynamic neurometabolic changes during spreading depolarization, ACS Chemical Neuroscience, 2013, 4 (5), pp 799–807,  doi:10.1021/cn400047x

4. A microdroplet dilutor for high-throughput screening, Nature Chemistry, 2011, Volume:3, (6), 437-442, doi:10.1038/NCHEM.1046